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Genehunter-Plus is a modification of the GENEHUNTER software package which produces output files containing the null and conditional distributions of the test statistic (in nullprobs.dat and probs.dat, respectively). These files can then be used as input to the KAC program which incorporates the allele sharing modeling for lodscores and likelihood ratio tests as developed by Kong and Cox (1997).
To run, type: ghp
ASM is a program which incorporates the allele sharing modeling for lodscores and likelihood ratio tests as developed by Kong and Cox (1997). To use ASM you must first have completed a non-parametric analysis using GENEHUNTER-PLUS (v1.1 or later). The GENEHUNTER-PLUS 'scan' command will produce two output files, "nullprobs.dat" and "probs.dat", containing information about the distribution of the test statistic; one under the null hypothesis, and the other conditional on the position and marker data for each kindred. ASM expects the presence of those two files in the directory in which it is being run.
User Manual for Genehunter-Plus