Bioinformatics Applications MERLIN - Multipoint Engine for Rapid Likelihood Inference

The merlin application is available to registered users only. If you aren't registered but would like to run this program using our facilities, Register Now!

Run merlin now!

Merlin is a new, efficient method for the analysis of dense genetic maps in pedigree data that provides extremely fast solutions to common problems such as allele-sharing analyses and haplotyping. Using an approximate multipoint calculation that ignores the unlikely possibility of a large number of recombinants further improves speed and provides accurate solutions in dense maps with thousands of markers. Our multipoint engine for rapid likelihood inference (Merlin) is a computer program that uses sparse inheritance trees for pedigree analysis; it performs rapid haplotyping, genotype error detection and affected pair linkage analyses and can handle more markers than other pedigree analysis packages.

Detailed description of merlin